Genistein mitigates diet-induced obesity and metabolic dysfunctions in gonadectomized mice with some sex-differential effects
BackgroundObesity is associated with insulin resistance (IR) and metabolic dysfunction-associated steatotic liver disease (MASLD).Genistein, an isoflavone, is a promising natural compound for preventing and treating obesity and metabolic dysfunctions.We aimed to investigate the sex-specific protective effects of genistein on obesity, IR, and MASLD